Tuesday, September 22, 2009

The Nocebo Effect

Everyone knows about the placebo effect, but this is the first time I'd heard about its evil twin, the nocebo effect: believing that you are ill can make you ill.

From New Scientist via Mind Power News...
Take Sam Shoeman, who was diagnosed with end-stage liver cancer in the 1970s and given just months to live. Shoeman duly died in the allotted time frame - yet the autopsy revealed that his doctors had got it wrong. The tumour was tiny and had not spread. "He didn't die from cancer, but from believing he was dying of cancer," says Meador. "If everyone treats you as if you are dying, you buy into it. Everything in your whole being becomes about dying."

Cases such as Shoeman's may be extreme examples of a far more widespread phenomenon. Many patients who suffer harmful side effects, for instance, may do so only because they have been told to expect them. What's more, people who believe they have a high risk of certain diseases are more likely to get them than people with the same risk factors who believe they have a low risk...

...The ultimate cause of the nocebo effect, however, is not neurochemistry but belief. According to Hahn, surgeons are often wary of operating on people who think they will die - because such patients often do. And the mere belief that one is susceptible to a heart attack is itself a risk factor. One study found that women who believed they are particularly prone to heart attack are nearly four times as likely to die from coronary conditions than other women with the same risk factors.

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